Hydrogen bonding in DNA

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NicoJones_1B
Posts: 49
Joined: Fri Aug 09, 2019 12:16 am

Hydrogen bonding in DNA

Postby NicoJones_1B » Fri Nov 08, 2019 6:37 pm

Why are the hydrogen bonding between the A and T base pairs stronger than the G, C base pairs?

Alan Wu
Posts: 61
Joined: Sat Sep 14, 2019 12:16 am

Re: Hydrogen bonding in DNA

Postby Alan Wu » Fri Nov 08, 2019 6:44 pm

Wait are you sure? Because in class we learned that there are 3 pairs of hydrogen bonds between G and C compared to 2 pairs between A and T. Therefore, G and C are harder to break apart.

Aadil Rehan 1D
Posts: 52
Joined: Thu Jul 11, 2019 12:16 am
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Re: Hydrogen bonding in DNA

Postby Aadil Rehan 1D » Fri Nov 08, 2019 6:46 pm

C-G pairs have three hydrogen bonds as opposed to A-T's two. I think the relative strength has to do with the lone pair donors and how they vary between the nitrogenous bases.
Last edited by Aadil Rehan 1D on Fri Nov 08, 2019 6:48 pm, edited 1 time in total.


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