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No you can only have limiting reactant in a reaction. Every other reactant is in excess. Once the ONE limiting reagent is completely used up, the particular reaction can no longer occur because the amount of product formed is limited by the limiting reagent. This is the case even if there is plenty of reactants left in excess.
By definition a limiting reactant is the reactant that will be completely consumed. There will be more of one than the other causing the reaction to stop there. Whatever is left of the reactants would be labeled as excess reactants. If the reactants are equal then they will not limit each other, rather they will both be used completely in the reaction.
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