Cellular Conditions vs Lab conditions

[Jasmine Tran 2A]

In gen bio, we learnt that the values of delta G and delta H could change depending on whether it was in a cell or a lab. Why would these values be different if the same reaction is occurring? i feel the difference would be in how quickly or efficiently the reaction occurs.

[Sisam Bhattarai 2C]

Due to various circumstances, the values of delta H (enthalpy) and delta G (Gibbs free energy) can fluctuate between a lab and a cell. Reactions with particular enzymes and cellular constituents frequently take place in a cell under physiological settings, which affects the reaction's efficiency and rate. Different regulated experimental circumstances in a lab can have an impact on the kinetics of reactions and overall energy changes.

[Evan Sang 1K]

I think temperature is a big difference between the two conditions, so that may affect things like reaction rate, etc.

[Alvin Au]

While the underlying chemical reaction may be the same in both cellular and laboratory settings, the surrounding conditions and regulatory mechanisms in cells can lead to differences in the thermodynamic and kinetic parameters of the reaction. Therefore, it's essential to consider the specific context in which a reaction occurs when interpreting its thermodynamic properties.