DNA structural transition and its deltaG

[Brian Xie 1H]

As the title suggests(*DNA Structural Transition, etc.), how is the structural transition of DNA related to anything we've learned in thermochemistry and thermodynamics? I guess that since it takes a certain amount of heat for DNA structure to be altered(denatured), some processes, like reactions in the body, can not release heat that is over a certain level in order not to make DNA structural transition happen and therefore avoid too much mutation. That is my narrow interpretation, so I'm asking this question. Also, other than coupling, what other biological examples can we apply thermochemistry and thermodynamics to? Incubation? Stem cell niche?

[Soumya 2D]

My best guess is that it affects dST because T can't be very large otherwise it will denature the DNA.

[Sam Lam]

A biological example could be The flow of energy into cells as you digest food or a similar one like photosynthesis