CHEMISTRY COMMUNITY

I heard Dr. Lavelle say multiple times that the closest you can get to estimating the delta G is by calculating the voltage difference, but I am kind of confused as to what this means and as to why this is true? If someone could explain it I would really appreciate it, thank you!

Perhaps he was referring to the electric potential, E. If delta E is positive, delta G will be negative. If delta E is negative, delta G will be positive.

I'm pretty sure since you are subtracting electric potential, a negative electric potential means that delta G is positive. So whatever the sign of the electric potential, delta G will always be the opposite