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You would have to make one reactant concentration small and the others large which makes the reaction rate dependent on only the small concentration reactant. Since they are such in large excess, they remain constant.
If you're given 2 experiments between two reactants A & B and there is one experiment that has both concentrations changing, solve for the order of reactant A first and then use that to help you find the order of reactant B (in the experiment which has both changing).
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