Determining all chiral carbons in a cyclic molecule

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Determining all chiral carbons in a cyclic molecule

Postby Chem_Mod » Tue Aug 30, 2011 1:20 am

Question: When you have a cyclic molecule how can you distinguish which carbons are chirality centers? For example, when looking at a cyclohexane, how do you determine the four different groups that a carbon is connected to, when it's such a big and cyclic compound? Do you just go one carbon out at a time, and look at the hybridization?

Chem_Mod
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Re: Determining all chiral carbons in a cyclic molecule

Postby Chem_Mod » Tue Aug 30, 2011 1:21 am

Answer: From the chiral C keep going and comparing one carbon at a time, until you find a difference. Then assign priority. Repeat until all four bonds around the chiral C are assigned.


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