Formal charges

[306520253]

Is it always better to have the central atom with a formal charge of 0 despite the other atoms within that molecule with a greater formal charge? Also if we are removing an electron due to cationic compound, do we always remove electrons from the outer atoms?

[RyanMcLaughlin_3J]

My understanding is that it is more stable for the central atom to have a fc of 0, especially because in a lot of cases the negative charge can dissociate across several outer atoms. In terms of removing an electron, I think in most cases the electron would come from the less electronegative atom.