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Having the resonance structure with formal charges closest to 0 (especially central atom) makes it the the structure with highest contribution. The f(c)=0 makes the molecule the most likely to react.
The center atom is the element with the lowest ionization energy so it would make sense for it to not have the negative charge. Since the atoms surrounding the center atom have higher ionization energy and electron affinity, they are more likely to carry the negative partial charge.
Any sort of charge on the central atom will cause the molecule to be less stable, meaning that it is not the best possible structure. For this reason, it is better to find another better structure that has the charge on one of the other atoms.
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