Polydentate Ligands

Moderators: Chem_Mod, Chem_Admin

Reina Robles 2B
Posts: 62
Joined: Fri Aug 09, 2019 12:16 am

Polydentate Ligands

Postby Reina Robles 2B » Fri Nov 29, 2019 7:45 pm

So I know polydentate ligands have multiple sites where they can bond to the same transition metal, but how do you know that it can do that? Thanks.

Anika Chakrabarti 1A
Posts: 86
Joined: Sat Aug 24, 2019 12:17 am

Re: Polydentate Ligands

Postby Anika Chakrabarti 1A » Fri Nov 29, 2019 8:24 pm

In the textbook, it says that the ligands ethylenediamine (en) and oxalato are bidentate, diethylenetriamine (dien) is tridentate, and (edta) is hexadentate. I'm not sure if these will always be polydentate though, or if it is only in certain cases.

EvanWang
Posts: 91
Joined: Sat Sep 07, 2019 12:16 am

Re: Polydentate Ligands

Postby EvanWang » Fri Nov 29, 2019 9:15 pm

It's tough to say but generally the bonding sites should be on the same side of the molecule. For example, cisplatin works because both of the Chlorines are on the same side and can bind to DNA at two points. If the Chlorines were in an orientation where they were opposite each other, the resulting molecule wouldn't effectively bind to DNA.

Reina Robles 2B
Posts: 62
Joined: Fri Aug 09, 2019 12:16 am

Re: Polydentate Ligands

Postby Reina Robles 2B » Sun Dec 08, 2019 9:19 am

Thank you both!


Return to “Naming”

Who is online

Users browsing this forum: No registered users and 1 guest