Heme & Porphyrin

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Brandon Valafar
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Heme & Porphyrin

Postby Brandon Valafar » Sun Dec 08, 2019 12:01 am

What is the difference between the heme complex and porphyrin and what do I need to know about each?

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Re: Heme & Porphyrin

Postby Julie_Reyes1B » Sun Dec 08, 2019 2:43 am

The porphyrin refers to the chelating ligand in the heme complex only, while the heme complex is the porphyrin ligand attached to the Fe (II). Porphyrin is a chelating ligand that is also tetradentate (meaning it bonds to the Fe at four different sites). The heme complex is square planar shaped. Beyond the 4 bonding sites with the porphyrin, the heme complex will bind with a protein to form myoglobin. The last of the 6 binding sites on the complex will attach to an O2 molecule. Read about the biological importance of myoglobin and hemoglobin (4 myoglobins) in the lecture notes as well.

Mai V 4L
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Re: Heme & Porphyrin

Postby Mai V 4L » Sun Dec 08, 2019 9:13 am

Do0es anyone have a video they think is a good reference for this topic?

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