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Being cis or trans is really dependent on the biological function of the molecule. Having a cis configuration is convenient for the cisplatin chemotherapy drug mentioned in class, but for a different compound with a trans configuration, it may prove to be more effective for its function.
If a polar bond is needed between molecules, then a cis molecule is preferred (it's polar). If the desire is to prevent polar bonds from forming, then a trans molecule is preferred (it's non-polar).
yea it depends on which is more beneficial in terms of polarity. If you want to have a nonpolar molecule with a zero dipole moment then do trans but if you want a polar molecule with a nonzero dipole moment, then cis.
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