Cis Trans Isomers

[Lusin_Yengibaryan_3B]

How heavily will the final on 12/14/20 focus on cis/trans isomers? Can someone please explain a little better the concept of cis/trans isomers and how to determine them?

[Hazelle Gunawan 3G]

I'm not sure how often they'll appear on the final, but cis is basically when you have the same element on the same side of the compound and trans is when they're on opposite sides (e.g. diagonal from each other).

[Evelyn Silva 3J]

An example you should know is cisplatin, which is a chemotherapy medication that has two Cl atoms on the same side. It bonds to two neighboring guanines and it stops DNA replication.

[Nancy Yao]

It did appear in the exam and I did it wrong highly possibly.

[Gustavo_Chavez_1K]

Cis isomers are when two of the same ions are on the same side. This means that there are dipole moments present in the isomer. Trans isomers are when the ions are on opposite sides. So this means that the dipole moments essentially cancel each other out.

[JTieu_1L]

cis on the same side and trans on opposite (molecules with lone pairs) - refer to cisplatin as an example

[205323697]

How would we determine if a molecule is a cis/trans isomer based on its name?

[allyssa bradley 1H]

How would we determine if a molecule is a cis/trans isomer based on its name?

The name always includes the prefix "cis" or "trans," as we learned in lecture when it came to naming! I wonder if it's not named, if it's sort of like resonance structure where multiple versions appear, or if it's always assigned.