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The syllabus for chapter 17 on the website says we need to know "well-known examples of coordination compounds used as chemotherapy drugs." Is this something he mentioned in a lecture or something in the textbook? I can't seem to find anything on it.
This was lectured on in class. The chemotherapy drug he referred to was Cisplatin. The long name for this drug is Cis-diamminedichloroplatinum (II), which contrasts with trans-diamminedicholoplatinum because of where the ammine or chloride groups are placed (next to or opposite of one another). Cisplatin forms a coordination compound with DNA and stops cell replication.
Also, the cis-diamminedichloroplatinum (II) can bind better to DNA due to the location of the chlorines. The lewis structure of this compound results in the chlorines on the same side (hence the name cis-) rather than opposite sides (trans-).
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