Transition metals

[Beatrice Petelo 1F]

Are we required to know the transition metals (such as Cr, Fe, Co, Mn, Ni, Cu, and Zn) and their functions for the final?

[Fayez Kanj]

Hey!

Yes, on the outline for the coordination compounds unit, it says to know some common biological examples and their functions. I think we need to know these:

1. EDTA (removes mineral ions from solution by reacting with them)
2. hemoglobin and myoglobin (oxygen transport in the blood and muscles respectively)
3. Chromium (Cr): assists insulin in control of blood sugar levels
4. Iron (Fe): used to produce myoglobin and hemoglobin, and helps with electron transfer in the respiratory chain
5. Cobalt (Co): Vitamin B12 component -- octahedral complex
6. Mn, Ni, Cu, Zn: critical for enzyme function (at the active site to allow substrate to bind)
7. Cisplatin: a well known chemotherapy drug that forms a coordination compound with a lone pair on the Guanine of DNA to stop cell division and can prevent tumor formation

Hope this helps :)

[becca_vandyke_4b]

You also need to know how to calculate their oxidation number in a compound since their oxidation number can differ.

[Danny Elias Dis 1E]

Is iron the only transition metal that can be transported using hemoglobin?