Biological Importance

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Biological Importance

Postby nolansheow3G » Thu Dec 06, 2018 5:25 pm

Can somebody explain the biological importance of coordination compounds and how these compounds actually influence biological systems?

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Joined: Fri Sep 28, 2018 12:17 am

Re: Biological Importance

Postby LuisG14A1J » Thu Dec 06, 2018 7:32 pm

Biological Importance of Coordination Compounds
TM(Transition Metals) have many oxidation states: Good for e- Transfer
TM Often Bound to a cage-like Molecule (Poly dentate Ligands)
E.g. Porphyrin Ligand: Tetradentate Square Planar 4N (Nitrogens)
Fe Bound to Porphyrin Ligand ---> Heme Complex

That's a direct copy and paste from my notes of the biological significance of the Compounds.
Another direct rip.
cis-diamine-dichloro-platinum(II) trans-diamine-dichloro-platinum(II)
Ci Next to each other | Ci Opposite of each other matters, it has tremendous biological significance because it was one of the very first chemotheropeutic drugs
Forms a coordination compound with DNA: stops cell division.

Last portion. Hope it helps.
Oxygen is absorbed or de-absorbed depending on the local partial pressure of oxygen.
Hemoglobin has 4 Myoglobin-like Molecules: Binds 4 O2 Transport of O2 in blood

NOTE: Most common shape for Transition Metal Compounds is OCTAhedral. 6 Ligand

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