Page 1 of 1

Heme Complex

Posted: Fri Nov 22, 2019 9:19 pm
by Lindsey Chheng 1E
Is Fe always at the center of a Heme Complex? I feel like he went into a lot of detail about the Heme Complex today. Will we have to know it in as much depth as he went over?

Re: Heme Complex

Posted: Fri Nov 22, 2019 10:26 pm
by Vincent Leong 2B
As far as conceptually, I think we need to understand its function and how its molecular components have a role in playing in its biological function. And yes, I feel like Fe is always at the center of the heme complex because you can think of it like drawing lewis structures, the least electronegative atom (out of Fe and N) is always at the center of the molecule.

Re: Heme Complex

Posted: Sat Nov 23, 2019 6:04 pm
by Alan Wu
Fe is always at the center of the Heme Complex. The reason he talked about the heme complex is because it is a coordination complex. And all coordination complexes are made up of a transition metal as the central atom, which is then bonded to numerous ligands.

Re: Heme Complex

Posted: Sat Nov 23, 2019 10:47 pm
by DHavo_1E
Hi,

Could someone reiterate the significance of Fe as the central atom in the Heme complex, and how that relates to its function? Thank you!

Re: Heme Complex

Posted: Sat Nov 23, 2019 11:40 pm
by Wilson 2E
A heme complex is the specific arrangement of a central Fe atom surrounded by 4 N atoms. If the central atom isn't Fe but is a different type of transition metal, then it isn't a heme complex but rather a different complex.

Re: Heme Complex

Posted: Sun Nov 24, 2019 9:33 am
by Shutong Hou_1F
DHavo_3H wrote:Hi,

Could someone reiterate the significance of Fe as the central atom in the Heme complex, and how that relates to its function? Thank you!


Hi there,
According to professor Lavelle's lecture and his slides:
The Fe atom plays a role in binding one oxygen molecule, and therefore could perform the function of transporting oxygen in muscle cells. Whether oxygen is absorbed or de-absorbed depends on the local partial pressure of oxygen.