cisplatin

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405404782 Gabriel Rigole 4F
Posts: 56
Joined: Sat Aug 17, 2019 12:18 am

cisplatin

Postby 405404782 Gabriel Rigole 4F » Sun Nov 24, 2019 4:36 pm

What are the pros and cons cisplatin when it comes to cancer treatment.

J Medina 2I
Posts: 102
Joined: Wed Sep 25, 2019 12:17 am

Re: cisplatin

Postby J Medina 2I » Sun Nov 24, 2019 4:39 pm

I think Lavelle mentioned in lecture that cisplatin not only stops cell division of cancer cells but stops division for all cells

Trent Yamamoto 2J
Posts: 111
Joined: Sat Aug 17, 2019 12:18 am

Re: cisplatin

Postby Trent Yamamoto 2J » Sun Nov 24, 2019 5:23 pm

Cisplatin forms a coordination compound with DNA, which stops the rapid and controllable cell division of cancer cells. However, it does not single out cancer cells specifically, and can stop the division of normal cells as well

Louise Lin 2B
Posts: 97
Joined: Sat Aug 17, 2019 12:15 am

Re: cisplatin

Postby Louise Lin 2B » Sun Nov 24, 2019 5:26 pm

The pros of cisplatin are that they kill cancer cells very effectively. A minor con is that cisplatin also works on healthy cells, but Dr. Lavelle mentioned that the degree at which they kill healthy cells is relatively less than the amount of cancer cells killed.

Elizabeth Johnson 1I
Posts: 53
Joined: Wed Sep 11, 2019 12:16 am

Re: cisplatin

Postby Elizabeth Johnson 1I » Sun Nov 24, 2019 5:26 pm

Are we expected to know this stuff for the class or is this forum more just about entertaining curiosity?

005162520
Posts: 101
Joined: Tue Sep 24, 2019 12:17 am

Re: cisplatin

Postby 005162520 » Sun Nov 24, 2019 8:57 pm

Yes, we are expected to know this for the class and discuss well known examples of coordination compounds that are used as chemotherapy drugs.

Jared Khoo 1G
Posts: 107
Joined: Wed Sep 18, 2019 12:16 am

Re: cisplatin

Postby Jared Khoo 1G » Fri Nov 29, 2019 9:47 pm

Does anyone remember what specific nucleotide Cisplatin attaches to?


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