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Cisplatin

Posted: Sun Nov 24, 2019 9:51 pm
by Andrea_1H
What did Dr. Lavelle say cisplatin does to normal, healthy cells?

Re: Cisplatin

Posted: Sun Nov 24, 2019 9:57 pm
by alex_4l
it's a form or chemotherapy to stop the growth of cancer cells, unfortunately it also impacts the healthy cells from multiplying. It usually impacts healthy cells that multiply quickly, such as hair and blood cells.

Re: Cisplatin

Posted: Sun Nov 24, 2019 10:08 pm
by Tiffany Dong_4e
It is used to stop cell division for cancer treatment, but it also stops healthy cell division.

Re: Cisplatin

Posted: Sun Nov 24, 2019 10:55 pm
by 305416361
Cisplatin can stop the division of cancer cells, however, it doesn't target cancer cells specifically, so it can potentially stop the division of normal, healthy cells.

Re: Cisplatin

Posted: Sun Nov 24, 2019 11:17 pm
by Lauren Sanchez 3D
Cisplatin stops the growth of cancer cells, but not exclusively, so it would also stop the growth of healthy cells.

Re: Cisplatin

Posted: Mon Nov 25, 2019 11:44 am
by Megan_1F
Cisplatin aims to stop cell division. However, it will affect cancer cells and healthy cells.

Re: Cisplatin

Posted: Mon Nov 25, 2019 1:25 pm
by Kelsey Ash 1D
It is a type of chemotherapy which stops cell division in an attempt to keep the cancerous cells from spreading. Unfortunately it also affects normal healthy cells' ability to multiply.

Re: Cisplatin

Posted: Mon Nov 25, 2019 2:05 pm
by Amy Pham 1D
It has two Cl's that bond with guanines in the DNA of fast-growing cells (both harmful and healthy), preventing them from replicating. This stops the cell division of both cancerous and healthy cells.

Re: Cisplatin

Posted: Mon Nov 25, 2019 2:11 pm
by Hannah Romano 4D
Cisplatin will bond to two nearby Guanine molecules on the DNA and prevent the DNA from being able to "unzip" for DNA replication. Thus without DNA replication a cell cannot divide will eventually die.

Re: Cisplatin

Posted: Mon Nov 25, 2019 2:34 pm
by Sean Sugai 4E
Cisplatin is used in chemotherapy to stop the growth of cancer cells. In the process, it damages DNA and prevents DNA synthesis, which in turn damage the healthy cells.

Re: Cisplatin

Posted: Sun Dec 08, 2019 8:04 pm
by alex_4l
Cisplatin also does this by replacing something in the guanine molecule with a water molecule so that DNA synthesis cannot occur

Re: Cisplatin

Posted: Sun Dec 08, 2019 8:34 pm
by Sean Sugai 4E
Cisplatin is a chemotherapy drug, and it binds to the nucleotides on DNA to stop cell growth; however, in doing so, it stops the production of normal cells.

Re: Cisplatin

Posted: Sun Dec 08, 2019 9:43 pm
by Lauren Lewis3L
Cisplatin is important because it stops cell division by attaching to DNA and most importantly Guanine.

Re: Cisplatin

Posted: Sun Dec 08, 2019 9:56 pm
by Kimberly Koo 2I
Cisplatin is able to attach to DNA and stop cell division, which is why it is used in treating cancer

Re: Cisplatin

Posted: Sun Dec 08, 2019 10:09 pm
by Michelle Chan 1J
It is more effective than transplatin because it binds twice instead of once making it more effective.

Re: Cisplatin

Posted: Sun Dec 08, 2019 10:55 pm
by Liliana Aguas 3G
Cisplatin is the biologically active one whereas trans is not due to the better job cis does from bonding at tow G on DNA rather than 1.

Re: Cisplatin

Posted: Sun Dec 08, 2019 10:59 pm
by Eesha Chattopadhyay 2K
Cisplatin is a helpful chemotherapy drug because it stops rapid cell division. However, it has recently stopped being used as frequently because of its inability to target malignant cells, meaning that rapidly dividing healthy cells (such as hair follicles) are also affected.

Re: Cisplatin

Posted: Sun Dec 08, 2019 11:26 pm
by san_2F
he just said that it affects normal healthy cells and either damages them or stops the replication fo them.