Porphyrin ligand-tetradentate

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Amy Kumar 1I
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Joined: Thu Jul 11, 2019 12:15 am

Porphyrin ligand-tetradentate

Postby Amy Kumar 1I » Sun Nov 24, 2019 10:16 pm

Can someone please example the porphyrin ligand-tetradentate example from lecture with relation to heme complexes?

GFolk_1D
Posts: 101
Joined: Fri Aug 09, 2019 12:15 am

Re: Porphyrin ligand-tetradentate

Postby GFolk_1D » Mon Nov 25, 2019 9:19 am

Here's what I gathered...
- it is an example of a cage-like molecule
- it is square planar
- Fe is bound to the porphyrin ligand to form a heme complex
- the heme complex plus a protein creates myoglobin (Fe binds to 1 O2)
- it plays a role in the transport of O2 in the muscle cells
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MeeraBhagat
Posts: 95
Joined: Sat Aug 24, 2019 12:15 am

Re: Porphyrin ligand-tetradentate

Postby MeeraBhagat » Sun Dec 01, 2019 12:34 pm

The heme complex is created by the binding of the porphyrin tetra dentate ligand to an iron ion. When a protein is bound, this creates myoglobin which is responsible for transport of oxygen throughout the bloodstream. This happens when an O2 molecule binds to the iron. Carbon Monoxide poisoning happens when a CO molecule binds to the iron instead of the O2 molecule, and this is essentially suffocation at the molecular level. This would probably be a good concept to know.


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