Chemotherapy

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Zoya Mulji 1K
Posts: 105
Joined: Thu Jul 11, 2019 12:15 am

Chemotherapy

Postby Zoya Mulji 1K » Sat Nov 30, 2019 7:45 pm

What are some examples of coordination compounds used as chemotherapy drugs?

gferg21
Posts: 51
Joined: Sat Aug 17, 2019 12:17 am

Re: Chemotherapy

Postby gferg21 » Sat Nov 30, 2019 7:49 pm

cisplatin and oxaliplatin are the most common chemotherapy drugs and have four ligands, meaning that they are often in a square planar structure or a tetrahedral structure.

Nare Nazaryan 1F
Posts: 101
Joined: Fri Aug 09, 2019 12:17 am

Re: Chemotherapy

Postby Nare Nazaryan 1F » Sun Dec 01, 2019 2:12 pm

Cisplatin is very common for chemotherapy.

Mariah
Posts: 104
Joined: Fri Aug 02, 2019 12:16 am

Re: Chemotherapy

Postby Mariah » Sun Dec 01, 2019 3:47 pm

Zoya Mulji 1F wrote:What are some examples of coordination compounds used as chemotherapy drugs?


I think we only need to know about cisplatin.

Jennifer Yang 3F
Posts: 56
Joined: Wed Sep 11, 2019 12:17 am

Re: Chemotherapy

Postby Jennifer Yang 3F » Mon Dec 02, 2019 1:42 am

I think we only have to know about cisplatin, which Dr. Lavelle went over in lecture.

205154661_Dis2J
Posts: 109
Joined: Wed Sep 18, 2019 12:21 am

Re: Chemotherapy

Postby 205154661_Dis2J » Mon Dec 02, 2019 5:13 pm

I think for class, we need to know mainly about Cisplatin, which binds to DNA to kill cancer cells.

Abby Soriano 1J
Posts: 103
Joined: Sat Aug 24, 2019 12:16 am

Re: Chemotherapy

Postby Abby Soriano 1J » Mon Dec 02, 2019 5:18 pm

I'm pretty sure we only need to know about cisplatin since Dr. Lavelle discussed it in detail. It's good to know how it works rather than just knowing what it's used for. The reason why cisplatin is a useful chemotherapy drug is that its two Cl ligands (which are on the same side) get displaced by exposed N's on guanine. The strong bond keeps the cells from dividing.


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