Coordination Compounds and Chemotherapy Drugs

Moderators: Chem_Mod, Chem_Admin

Lauren Haight 1E
Posts: 73
Joined: Wed Sep 18, 2019 12:15 am
Been upvoted: 1 time

Coordination Compounds and Chemotherapy Drugs

Postby Lauren Haight 1E » Sat Nov 30, 2019 8:32 pm

Which coordination compounds did Dr. Lavelle give as examples of coordination compounds used as chemotherapy drugs?

Juliet Stephenson 4E
Posts: 100
Joined: Wed Sep 18, 2019 12:21 am

Re: Coordination Compounds and Chemotherapy Drugs

Postby Juliet Stephenson 4E » Sat Nov 30, 2019 8:34 pm

I can't remember what the full name of the compound is but the drug is called cisplatin, and if you feel like googling that, it should yield more information regarding the full name of the coordination compound.

Amanda Lin 2I
Posts: 101
Joined: Sat Aug 17, 2019 12:15 am

Re: Coordination Compounds and Chemotherapy Drugs

Postby Amanda Lin 2I » Sat Nov 30, 2019 8:36 pm

He talked about cisplatin or cis-diammine-dichloro-platinum(II).

TheresaDsilva4A
Posts: 53
Joined: Thu Jul 25, 2019 12:17 am

Re: Coordination Compounds and Chemotherapy Drugs

Postby TheresaDsilva4A » Sun Dec 01, 2019 2:00 pm

Does anyone know what information we have to specifically know about these chemotherapy drugs? Is it just that they're an example of a coordination compound? I was absent during this lecture, so I'd appreciate any information! Thank you so much :)

Amina Durrani 3G
Posts: 52
Joined: Sat Jul 20, 2019 12:16 am

Re: Coordination Compounds and Chemotherapy Drugs

Postby Amina Durrani 3G » Sun Dec 01, 2019 2:04 pm

In lecture, Lavelle said that cisplatin forms a coordination compound with DNA (Pt bonds with N in NH3) and this stops cell division (replication inhibition, transportation inhibition, cell cycle arrest, dna repair, and cell death).

305416361
Posts: 50
Joined: Fri Aug 09, 2019 12:17 am

Re: Coordination Compounds and Chemotherapy Drugs

Postby 305416361 » Wed Dec 04, 2019 8:47 am

TheresaDsilva4A wrote:Does anyone know what information we have to specifically know about these chemotherapy drugs? Is it just that they're an example of a coordination compound? I was absent during this lecture, so I'd appreciate any information! Thank you so much :)


I think the main thing we need to know about cisplatin is that it stops the replication of cancerous cells by forming a coordination compound with DNA; however, cisplatin does not specifically target cancer cells, and can therefore also stop the replication of normal and healthy cells.


Return to “Biological Examples”

Who is online

Users browsing this forum: No registered users and 1 guest