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Carbon Monoxide and Oxygen bound to hemoglobin?

Posted: Tue Dec 03, 2019 9:42 am
by Ada Chung 1C
Can someone explain why carbon monoxide is capable of binding stronger than O2 in the hemoglobin example that was talked about in Week 8's lecture?

Re: Carbon Monoxide and Oxygen bound to hemoglobin?

Posted: Tue Dec 03, 2019 11:32 am
by Amanda Lin 2I
The affinity of CO binding to hemoglobin is stronger than the affinity between O2 and hemoglobin.

Re: Carbon Monoxide and Oxygen bound to hemoglobin?

Posted: Wed Dec 04, 2019 8:50 pm
by Milisuryani Santoso 1L
Its essentially an irreversible process when CO binds to hemoglobin, whereas O2 isn't because it's affinity to bind to heme is much stronger than the O2 molecule.