Cisplatin bonding in 2 places

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Malia Shitabata 1F
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Joined: Sat Aug 17, 2019 12:17 am

Cisplatin bonding in 2 places

Postby Malia Shitabata 1F » Thu Dec 05, 2019 10:24 pm

Cisplatin can bond in 2 places because the chlorine atoms are easily displaced. Does this mean it chelates when it bonds with DNA?

Connor Ho 1B
Posts: 102
Joined: Sat Aug 17, 2019 12:17 am

Re: Cisplatin bonding in 2 places

Postby Connor Ho 1B » Fri Dec 06, 2019 11:51 am

I believe so, and I believe this means cisplatin in is bidentate.

Bradley Whitworth 4B
Posts: 54
Joined: Sat Jul 20, 2019 12:17 am

Re: Cisplatin bonding in 2 places

Postby Bradley Whitworth 4B » Fri Dec 06, 2019 9:09 pm

Yes, the mobility should mean it's chelating.

005162520
Posts: 101
Joined: Tue Sep 24, 2019 12:17 am

Re: Cisplatin bonding in 2 places

Postby 005162520 » Sat Dec 07, 2019 10:26 am

How do we know that the chlorine atoms are displaced?


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