Hemoglobin

[Tracey Tran 3I]

How is hemoglobin made?

[JOtomo1F]

Hemoglobin is formed when four myoglobin molecules bond together.

[JOtomo1F]

The porphyrin ligand bonds to Fe which forms the heme complex. When the heme complex binds to a protein, it forms myoglobin where Fe can bind to one oxygen (O2) molecule. To make hemoglobin, four myoglobins can bind together.

[Jielena_Bragasin2G]

The heme complex is the porphyrin ligand connected to a Fe2+. With a protein and an O2 attached Fe2+, this will become a myoglobin. Four myoglobin will create the whole hemoglobin. To help you remember it is heme complex > myoglobin > hemoglobin.

[Martina]

Four myoglobin create a hemoglobin, and each myoglobin can carry one oxygen. So total 4 can be carried by a hemoglobin.