Biological Function

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Biological Function

Postby briannam_1F » Sun Dec 08, 2019 10:08 pm

What atom was it exactly that was displaced by cisplatunum.

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Re: Biological Function

Postby Jared_Yuge » Sun Dec 08, 2019 10:20 pm

It kinda just squeezes itself into the H-N hydrogen bond in the backbone between two guanine or two adenine, causing a kink that prevents DNA replication

Natalie Wang 1B
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Re: Biological Function

Postby Natalie Wang 1B » Sun Dec 08, 2019 10:53 pm

Cis platinum chelates a nitrogenous base and blocks DNA replication.

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