Biological Function

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briannam_1F
Posts: 35
Joined: Wed Sep 18, 2019 12:18 am

Biological Function

Postby briannam_1F » Sun Dec 08, 2019 10:08 pm

What atom was it exactly that was displaced by cisplatunum.

Jared_Yuge
Posts: 100
Joined: Sat Aug 17, 2019 12:17 am

Re: Biological Function

Postby Jared_Yuge » Sun Dec 08, 2019 10:20 pm

It kinda just squeezes itself into the H-N hydrogen bond in the backbone between two guanine or two adenine, causing a kink that prevents DNA replication

Natalie Wang 1B
Posts: 51
Joined: Sat Sep 14, 2019 12:15 am
Been upvoted: 1 time

Re: Biological Function

Postby Natalie Wang 1B » Sun Dec 08, 2019 10:53 pm

Cis platinum chelates a nitrogenous base and blocks DNA replication.


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