O2 Transport
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O2 Transport
Hi, could someone clarify how myoglobin or heme complexes play a part in O2 transport in the body?
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Re: O2 Transport
The central Fe in the heme complex is octahedral: bound at four sites to square planar porphyrin ligand and one axial bond to histidine. So, it has a free spot (opposite to the histidine) that O2 can bind to and unbind to. This allows the heme complex to transport one O2 molecule.
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Re: O2 Transport
These complexes can carry oxygen because the central atom of a myoglobin complex has one space for oxygen to bind to. 4 spots are taken by ligands, and one by an amino acid, leaving one space to carry oxygen. This is because Fe will make 6 bonds.
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Re: O2 Transport
A porphyrin ligand is tetradentate. When the N attach to the Fe, it forms a heme complex which is square planar. Fe has 4 bonds at this point. Then, a protein attaches to the Fe making it so that the Fe has 5 bonds now. This is myoglobin which is found in muscle. It can pick up an O2 to form 6 bonds with Fe. Thus, myoglobin is able to carry blood throughout muscle.
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Re: O2 Transport
Aida Fraser 2I wrote:so hemoglobin can carry 4 oxygens?
Yes, a hemoglobin can carry/bond with 4 oxygens because it consists of 4 myoglobin (each of which can carry 1 oxygen)
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Re: O2 Transport
arielle_cunanan_1B wrote:Aida Fraser 2I wrote:so hemoglobin can carry 4 oxygens?
Yes, a hemoglobin can carry/bond with 4 oxygens because it consists of 4 myoglobin (each of which can carry 1 oxygen)
thank you!
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