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After you do the ICE box method and find the equilibrium concentrations, you divide the equilibrium concentration of the conjugate acid or base by the initial concentration of the acid or base given and multiply that by 100. For example, if the chemical reaction was CH3COOH + H2O --> CH3COO- + H3O+, then the percent ionization would be [CH3COO-]/[CH3COOH] times 100.
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