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You can find the bond enthalpies of the reactants and products involved in breakage/forming of bonds in the reaction and then add those enthalpies to find the total enthalpy of the reaction. You can also calculate (total enthalpy of products) - (total enthalpy of reactants) which will yield the total enthalpy change of the reaction.
There are 3 methods he described in class. You can add the bond enthalpies between the molecules and do broken - formed. If you have 2 reactions, you can add up the enthalpies to find the enthalpy of reaction for the combined one. Finally, you can use the enthalpy of formation to find it (products - reactants).
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