Cisplatin

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Andrea_1H
Posts: 50
Joined: Wed Sep 18, 2019 12:18 am

Cisplatin

Postby Andrea_1H » Sun Nov 24, 2019 9:51 pm

What did Dr. Lavelle say cisplatin does to normal, healthy cells?

alex_4l
Posts: 109
Joined: Thu Sep 26, 2019 12:18 am

Re: Cisplatin

Postby alex_4l » Sun Nov 24, 2019 9:57 pm

it's a form or chemotherapy to stop the growth of cancer cells, unfortunately it also impacts the healthy cells from multiplying. It usually impacts healthy cells that multiply quickly, such as hair and blood cells.

Tiffany Dong_4e
Posts: 51
Joined: Wed Sep 11, 2019 12:17 am

Re: Cisplatin

Postby Tiffany Dong_4e » Sun Nov 24, 2019 10:08 pm

It is used to stop cell division for cancer treatment, but it also stops healthy cell division.

305416361
Posts: 50
Joined: Fri Aug 09, 2019 12:17 am

Re: Cisplatin

Postby 305416361 » Sun Nov 24, 2019 10:55 pm

Cisplatin can stop the division of cancer cells, however, it doesn't target cancer cells specifically, so it can potentially stop the division of normal, healthy cells.

Lauren Sanchez 3D
Posts: 52
Joined: Sat Aug 24, 2019 12:17 am

Re: Cisplatin

Postby Lauren Sanchez 3D » Sun Nov 24, 2019 11:17 pm

Cisplatin stops the growth of cancer cells, but not exclusively, so it would also stop the growth of healthy cells.

Megan_1F
Posts: 49
Joined: Thu Jul 25, 2019 12:16 am

Re: Cisplatin

Postby Megan_1F » Mon Nov 25, 2019 11:44 am

Cisplatin aims to stop cell division. However, it will affect cancer cells and healthy cells.

Kelsey Ash 1D
Posts: 50
Joined: Wed Sep 18, 2019 12:16 am

Re: Cisplatin

Postby Kelsey Ash 1D » Mon Nov 25, 2019 1:25 pm

It is a type of chemotherapy which stops cell division in an attempt to keep the cancerous cells from spreading. Unfortunately it also affects normal healthy cells' ability to multiply.

Amy Pham 1D
Posts: 103
Joined: Fri Aug 09, 2019 12:15 am

Re: Cisplatin

Postby Amy Pham 1D » Mon Nov 25, 2019 2:05 pm

It has two Cl's that bond with guanines in the DNA of fast-growing cells (both harmful and healthy), preventing them from replicating. This stops the cell division of both cancerous and healthy cells.

Hannah Romano 4D
Posts: 55
Joined: Sat Aug 24, 2019 12:18 am

Re: Cisplatin

Postby Hannah Romano 4D » Mon Nov 25, 2019 2:11 pm

Cisplatin will bond to two nearby Guanine molecules on the DNA and prevent the DNA from being able to "unzip" for DNA replication. Thus without DNA replication a cell cannot divide will eventually die.

Sean Sugai 4E
Posts: 56
Joined: Wed Sep 11, 2019 12:17 am

Re: Cisplatin

Postby Sean Sugai 4E » Mon Nov 25, 2019 2:34 pm

Cisplatin is used in chemotherapy to stop the growth of cancer cells. In the process, it damages DNA and prevents DNA synthesis, which in turn damage the healthy cells.

alex_4l
Posts: 109
Joined: Thu Sep 26, 2019 12:18 am

Re: Cisplatin

Postby alex_4l » Sun Dec 08, 2019 8:04 pm

Cisplatin also does this by replacing something in the guanine molecule with a water molecule so that DNA synthesis cannot occur

Sean Sugai 4E
Posts: 56
Joined: Wed Sep 11, 2019 12:17 am

Re: Cisplatin

Postby Sean Sugai 4E » Sun Dec 08, 2019 8:34 pm

Cisplatin is a chemotherapy drug, and it binds to the nucleotides on DNA to stop cell growth; however, in doing so, it stops the production of normal cells.

Lauren Lewis3L
Posts: 57
Joined: Wed Feb 20, 2019 12:16 am

Re: Cisplatin

Postby Lauren Lewis3L » Sun Dec 08, 2019 9:43 pm

Cisplatin is important because it stops cell division by attaching to DNA and most importantly Guanine.

Kimberly Koo 2I
Posts: 99
Joined: Sat Aug 17, 2019 12:17 am

Re: Cisplatin

Postby Kimberly Koo 2I » Sun Dec 08, 2019 9:56 pm

Cisplatin is able to attach to DNA and stop cell division, which is why it is used in treating cancer

Michelle Chan 1J
Posts: 50
Joined: Thu Jul 25, 2019 12:16 am

Re: Cisplatin

Postby Michelle Chan 1J » Sun Dec 08, 2019 10:09 pm

It is more effective than transplatin because it binds twice instead of once making it more effective.

Liliana Aguas 3G
Posts: 59
Joined: Wed Sep 18, 2019 12:20 am

Re: Cisplatin

Postby Liliana Aguas 3G » Sun Dec 08, 2019 10:55 pm

Cisplatin is the biologically active one whereas trans is not due to the better job cis does from bonding at tow G on DNA rather than 1.

Eesha Chattopadhyay 2K
Posts: 104
Joined: Fri Aug 09, 2019 12:16 am

Re: Cisplatin

Postby Eesha Chattopadhyay 2K » Sun Dec 08, 2019 10:59 pm

Cisplatin is a helpful chemotherapy drug because it stops rapid cell division. However, it has recently stopped being used as frequently because of its inability to target malignant cells, meaning that rapidly dividing healthy cells (such as hair follicles) are also affected.

san_2F
Posts: 118
Joined: Sat Jul 20, 2019 12:15 am

Re: Cisplatin

Postby san_2F » Sun Dec 08, 2019 11:26 pm

he just said that it affects normal healthy cells and either damages them or stops the replication fo them.


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