Biological examples of co-ordination compounds

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Dakota Walker 1L
Posts: 58
Joined: Wed Sep 18, 2019 12:17 am

Biological examples of co-ordination compounds

Postby Dakota Walker 1L » Sun Dec 01, 2019 5:00 pm

Do we need to know specific examples and how they work for the final?
If so does anyone know which specific molecules we need to memorize?

Andrew Jang 4D
Posts: 50
Joined: Sat Aug 17, 2019 12:18 am

Re: Biological examples of co-ordination compounds

Postby Andrew Jang 4D » Sun Dec 01, 2019 5:09 pm

I feel like being conceptually aware of the significance of coordination compounds in biology will be more useful than memorizing specific examples. I do remember him talking about cisplatin and how it's an important chemo drug as it forms a coordination compound w/ DNA to stop replication.

gabbymaraziti
Posts: 111
Joined: Wed Sep 18, 2019 12:19 am

Re: Biological examples of co-ordination compounds

Postby gabbymaraziti » Sun Dec 01, 2019 5:15 pm

Prof. Lavelle did spend a significant amount of time on cisplatin, so I think we should understand that and the distinction between cis and trans.

EMurphy_2L
Posts: 128
Joined: Sat Sep 07, 2019 12:16 am

Re: Biological examples of co-ordination compounds

Postby EMurphy_2L » Sun Dec 01, 2019 5:16 pm

what we've talked about is
-cisplatin (chemo drug in which only cis- molecule, not trans- will connect)
-myglobin (square planar N with Fe + protein surrounding it)
-hemoglobin (4 myoglobin-like molecules)

and he put on the board these transition metals:
-chromin (assists insulin in controlling blood sugar)
-iron (electron transfer in oxidation of organic molecules, respiratory chain)
-cobalt (vitamin B12)
-Mn, Ni, Cu, Zn (enzyme function)


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