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I feel like there should always be an excess of one reactant which in return will cause the other reactant to become limited, so no I don't think its possible. A real-life example would be eating a bowl of cereal where you might put more milk than cereal and in the end, the bowl would be left with milk(excess reactant) and no cereal(limiting reactant). Hope this helps.
You can have tow limiting reactants, but only if when both run out at the same time, meaning they both hit 0 amount left as soon as these reactants are reacted away with available reactants.
However, the case where there are two limiting reactants is pretty rare - most chemistry problems will result in only one limiting reactant. (It also doesn't happen often in real life, because experiments usually put one reactant in excess.)
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